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PMPN NEWSLETTER

 
Volume 5, Issue 8 - August 18, 2006
Dynic USA Corp. - a leading manufacturer of high-quality thermal-transfer ribbons

Paxonix-a Mead Westvaco company, the provider of PaxPro software for 21CFR Part 11 compliance

RFID Applications-bringing you four specific applications of advanced track & trace solutions

Preserving the Personal Touch
In Drug Sampling

By David Vaczek

Physicians and consumers favor traditional sampling practices, even though e-sampling solutions are providing alternative channels for sample ordering and for disbursement of vouchers and coupons. And though inefficient distribution often leaves doctors with too few or too many samples, drug firms' spending on sampling has not diminished. These findings were reported by speakers at the recent Healthcare Compliance Packaging Council's Annual National Symposium on Patient Compliance.

"When the PDMA rules [requiring the tracking of sample distribution] went into effect in 1988, there was a lot of discussion about getting out of sampling. But industry, if anything, has increased its sampling," reported Ronald Buzzeo, the chief regulatory officer at BuzzeoPDMA (Richmond, VA).

Conference panelists said that e-sampling is gaining momentum in supporting cost-effective sample targeting and tracking. Marketers for example, can attract physicians by bundling e-sampling with resources such as e-detailing and continuing medical education (eCME). Consumers will print out more sample vouchers as they engage online resources for healthcare information. Pharmacies can then capture voucher redemption data providing marketers with insights on sample disbursement.

Yet doctors and consumers appear to be committed to traditional methods. Doctors prefer to have samples delivered by sales reps. And sample packets handed out by physicians often influence whether patients will fill a prescription, according to survey results presented by DataMonitor (New York City).

Fully 60% of doctors want to get samples through personal sales visits. Only 20% favor printing vouchers for patients to take to pharmacies, and just 10% prefer validating vouchers printed out by patients, the survey found.

Though 40% of doctors said they prefer to order sample packets over the Internet, this may be largely contingent behavior. Fully 71% of doctors cited too few drug samples and unpredictable supply as drawbacks of traditional sampling.

"Ordering samples online is becoming more common to make up for gaps in supply. Voucher use by doctors and consumers is much less common than Internet ordering, because it is not really getting at the problem of unsteady sample supply," said DataMonitor ehealth analyst Kim O'Malley said.

"We will see sample vouchers and coupons playing a bigger role, but it is not based [today] on physician or consumer demand. What we are seeing is a trend by doctors toward "making do" [with vouchers] when the preferred option isn't available," she adds.

The Association of American Medical Colleges this year weighed in on the side of healthcare groups that oppose sampling, terming samples "a powerful inducement for physicians and patients to rely on medications that are expensive, but not more effective."

Yet many physicians favor samples for establishing patient relationships, for reducing patients' costs, and for starting off therapy. DataMonitor found that sample packets are among the top factors affecting doctors' prescribing. While less influential than patient histories and formulary lists, they outweigh sales rep presentations, patient requests, and e-detailing.

Samples have a pronounced effect on prescription-filling behavior. When consumers were asked under what circumstances they would be most likely to fill a script, 30% said they would most likely fill it if they received a drug sample from the physician. (Fifty-seven percent said they would fill it regardless of how they received the drug.) Only 10% said a voucher from a doctor would influence them, and even fewer would be swayed by self-printed vouchers.

What are the prospects for making sample distribution to consumers more efficient? Samples are not used efficiently when doctors use them to provide a course of therapy, and they are wasted on patients that would fill a prescription anyway. DataMonitor analyzed consumer responses based on factors including age, gender, employment, income, and wellness. It found "no difference" between the groups prone to fill a script regardless of how they receive the drug, and those most likely to fill a script with a sample.

O'Malley says that eHealth records that progressively capture patients' medical histories and incorporate ePrescribing records will support sample targeting by individual.

"Doctors will make decisions based on the patient's prescription filling record and individual health record, tracking past behavior through time on a patient-by-patient basis. We will see a lot of money going into behavioral research. Medical students will be taught to recognize signs of compliance and non-compliance, and how to pro-actively address these," O'Malley says.

As drug marketers sustain their sample spending, contract packagers are devising solutions to support DTC programs. Howell Packaging (Elmira, NY) prints a unique access code under a zip strip on each individual sample wallet in a solution it is developing with several pharma firms, says Joseph Lally, marketing manager, packaging for pharmaceuticals.

The code permits one-time access to a secure Web site where the patient would establish a password for future access. Through the Web site, brand managers can provide the patient with support materials relative to the therapeutic category, and engage in permission-based marketing.

"This concept aligns well tactically with the shift of pharmaceutical DTC spending to support Internet strategies. Patients feel more comfortable using and exchanging personal information on the secure, limited access site. You are building a Web audience of the most important type-a group that has opted to be marketed to," he says.

Using e-sampling solutions, drug marketers can surmount the hurdle of inefficient sample distribution, providing that doctors are willing to participate in e-marketing programs. E-sampling will likely grow as an alternative distribution channel, since doctors' Web use is rapidly advancing in other areas, such as research and e-prescribing. Yet drug marketers will not relinquish the opportunity for sales reps to engage doctors on drug benefits. And physicians and consumers seem to value the opportunities that derive from traditional sampling methods.

Read the Current
issue of PMP News

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David Vaczek
Editor

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Material of the Month

Anticounterfeiting Carton

A company offers a carton featuring coin-reactive ink, a holographic foil stamp, and thermochromatic ink. All of these features can be applied in a single pass through the company's Gallus KM 510 folding carton press. The company offers these anticounterfeiting features as a lower-cost alternative to RFID technology. The company provides cartons with two-sided flexographic printing, die-cutting, screen printing, foil stamping, film lamination, and UV and water-based inks and coatings for many uses. Cadmus Healthcare Packaging, Charlotte, NC; 704/583-6561; www.cadmuswhitehall.com.

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A company offers a vision inspection machine for in-line operations involving bar codes, matrix codes, blemish checking, OCR/OCV, matching codes, and text quality. The LVS 7000 can also provide sequential and random number-checking and date and lot code verification. It can be mounted on a press or an inspection station. The machine is designed to run at line speed with interface to the host system. Label Vision Systems Inc., Peachtree, GA; 770/487-6414; www.lvs-inc.com.

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